ASP: Multilingual web sites (AddHeader, CodePage and CharSet)

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I've been working with multilingual web sites for a long time and - believe me - they sometimes are not so easy to manage. At the moment, one of the sites I manage, lets the user choose between 8 languages (including Cyrillic).
One of the issues you might have to face when dealing with languages, is how to manage charsets. I know there's a lot of talking about it, especially in relation to specific browsers and characters rendering. The only thing I remember is that it was a real pain! Being completely sure on how the web page was rendered seemed to be almost impossible.